The kit consists of a twosyringe mixing system, a sterile needle or a sterile safety needle table 2, a silica gel desiccant pouch to control moisture uptake, and a package insert for constitution and administration procedures. Mar 26, 2020 eligard is an injectable suspension of leuprolide acetate available in a singledose kit. Syringe a contains the atrigel delivery system and the syringe b contains leuprolide acetate powder. Learn how to prepare and administer eligard leuprolide. Niosh list of antineoplastic and other hazardous drugs in. Gently insert the long, white replacement plunger rod into. The reconstituted vaccine should be an opalescent, colorless to pale brownish liquid. Reactions may include hypotension, dyspnea, upper airway edema, lip swelling, rash, pruritus, and urticaria.
Eligard leuprolide acetate is indicated for the palliative treatment of advanced prostate. Eligard 45 mg powder and solvent for solution for injection. Insert the needle into the skin at a 45 degree angle all the way to the hub. Firmagon degarelix for injection is a prescription medicine used in the treatment of advanced prostate cancer. Dpi drug package insert epa environmental protection agency. Insert the syringe needle into the vial through the center of the stopper and direct the stream of sterile water for injection to the glass wall of the vial to avoid excessive foaming. Lupron depot, lupron depot ped, eligard leuprolide. Ndc 0143992390 cefazolin for injection, usp 500 mgvial for iv or im use rx only each vial contains sterile cefazolin sodium equivalent to 500 mg cefazolin.
This product is a type of hormonal therapy known as luteinizing hormonereleasing hormone lhrh agonist and. Our experts will verify insurance benefits and assist with prior authorizations, appeals, billing and. Mar 01, 2020 eligard is an injectable suspension of leuprolide acetate available in a singledose kit. Depot, lupron depot ped, eligard leuprolide suspension. Page 2 lupron depot, lupron depotped, eligard leuprolide prior auth criteria proprietary information. The kit consists of a twosyringe mixing system, a sterile safety needle table 3, a desiccant, and a package insert for reconstitution and administration procedures. Highlights of prescribing information hyperglycemia and. This label reflects clinical trials for lupron depot in prostate cancer in which the majority of the subjects studied were at least 65 years of age. Do not pull the back stopper flange off of the syringe. Insert the plunger rod into the prefilled syringe containing sterile water, usp, and screw the plunger rod clockwise to tighten. Zoladex is indicated for the management of endometriosis, including pain relief and reducing endometrial lesions, for 6 months of therapy. Eligard injectable suspension is used in men to treat the symptoms of prostate cancer eligard treats only the symptoms of prostate cancer and does not treat the cancer itself.
Dailymed cefazolin injection, powder, for solution. It works by reducing the amount of testosterone in the blood. Highlights of prescribing information hyperglycemia. Lupron depot leuprolide acetate for depot suspension. Apr 26, 2019 eligard is administered subcutaneously and provides continuous release of leuprolide acetate over a one, three, four, or sixmonth treatment period table 1. How to use eligard 45 mg 6 month subcutaneous syringe. Minimum ppe required handling only no alteration contained crushsplit crushsplit minimum ppe required abacavir susp 2 ziagenepzicomtrizivir low abacavir tablet 2 ziagenepzicomtrizivir universal low moderate acitretin capsule 3 soriatane universal moderate anastrazole tablet 1 arimidex low moderate high android capsule 3 methyltestosterone universal moderate. The member will receive eligard concomitantly with cross sex hormones. The most common injection site adverse events are transient burning and stinging, pain, bruising, and erythema. Gently insert the long, white replacement plunger rod into the gray. Dec 12, 2018 ndc 0143992390 cefazolin for injection, usp 500 mgvial for iv or im use rx only each vial contains sterile cefazolin sodium equivalent to 500 mg cefazolin. All patients who enrolled in the titan study started adt for mcspc. Every page of the record is expected to be legible and include.
Eligard should not be used by anyone who is allergic to any of the ingredients in eligard or to any medicines that reduce testosterone the same way. Gently swirl the vial for at least 15 seconds to dissolve the lyophilized powder. The total deliverable injection weight per dose is 375 mg including 45 mg of leuprolide acetate. Lupron depot is a prescription medication that must be administered in your doctors office. For detailed information on lupron depot, click on a link below. Zoladex is also approved to thin the lining of the uterus i. Eligard is indicated for the palliative treatment of advanced prostate cancer. Eligard may impair fertility in males of reproductive potential.
Eligard leuprolide acetate for injectable suspension, for subcutaneous use. Unscrew the gray syringe plug from the luer lock adaptor on. Highlights of prescribing information these highlights do not include all the information needed to use gleevec safely and effectively. Leuprolide reduces the amount of testosterone in men or estrogen in women. T ab l e1 i st dv rc onw h f5% g, cu sl ity, fr o mhe nd s1 p gfa lodex5 0 intramuscularly once a month with faslodex 250 mg intramuscularly once a month. Eligard must be brought to room temperature before mixing. Eligard overstimulates the bodys own production of certain hormones, which causes that production to shut down temporarily. When reconstituted, eligard is administered as a single dose. Stay focused on patients, not paperwork, with tolmarsync. Leuprolide prescribing information states that prior to initiation of treatment, a clinical diagnosis. Eligard is an injectable suspension of leuprolide acetate available in a singledose kit. Eligard delivery system composition and constituted product formulation.
Eligard s subcutaneous injection allows for numerous injection sites contributing to the patients comfort level. Xgeva includes the same active ingredient denosumab found in prolia. The kit consists of a twosyringe mixing system, a sterile needle table 2, a silicone desiccant pouch to control moisture uptake, and a package insert for constitution and administration procedures. Eligard leuprolide acetate for injectable suspension official. Eligard package insert pdf eligard leuprolide acetate is indicated for the palliative due to incorrect reconstitution or administration of the product see monitoring and. It is designed to deliver leuprolide acetate at a controlled rate over a 1, 3, 4, or 6month therapeutic period. Eligard palliative treatment of advanced prostate cancer. Injection, leuprolide acetate for depot suspension, per 3. Eligard leuprolide acetate for injectable suspension. Highlights of prescribing information these highlights do not include all the information needed to use zoladex safely and effectively. Full prescribing information 1 indications and usage copaxone is indicated for the treatment of relapsing forms of multiple sclerosis ms, to include clinically isolated syndrome, relapsingremitting disease, and active secondary progressive disease, in adults.
You will only feel light resistance when screwing the plunger rod into position. Advanced prostate cancer treatment firmagon degarelix for. Lupron depot leuprolide acetate for depot suspension initial u. Gently pull back the plunger to check if blood is aspirated. Use only the supplied adjuvant suspension component liquid for reconstitution. Saphris 5 mg tablets, black cherry flavor, are round, white to offwhite sublingual tablets, with 5 on one side within a circle. For healthcare professionals package insert about tolmar contact us. The injection delivers the dose of leuprolide acetate incorporated in a polymer formulation. Eligard fda prescribing information, side effects and uses.
Eligard is indicated for the palliative treatment of. Eligard is contraindicated in patients with hypersensitivity to luteinizing hormonereleasing hormone lhrh, lhrh analogs or any of the components of eligard. These highlights do not include all the information. By connor th, mackenzie ba, debord dg, trout db, ocallaghan jp. Gleevec imatinib mesylate tablets, for oral use initial u. Niosh list of antineoplastic and other hazardous drugs in healthcare settings, 2016. Eligard is an injectable suspension of leuprolide acetate available in a single use kit. All members including new members requesting authorization for continuation of therapy must meet all initial authorization criteria. Minimum ppe required ppe requirements hazardous drug handling. Salivary gland tumors authorization of 12 months may be granted for treatment of metastatic salivary gland tumors when the. Do not take firmagon if you are allergic to any of the ingredients in firmagon.
Dec 29, 2019 eligard package insert pdf eligard leuprolide acetate is indicated for the palliative due to incorrect reconstitution or administration of the product see monitoring and. Discontinue the injection and discard the syringe and the needle reconstitute a new dose for the patient. Eligard is a sterile polymeric matrix formulation of leuprorelin acetate for subcutaneous package insert for constitution and administration procedures. Minimum ppe required ppe requirements hazardous drug. Highlights of prescribing information these highlights do not include all the information needed to use lupron depot safely and effectively. The kit consists of a twosyringe mixing system, a sterile needle table 2, a silicone desiccant pouch to control moisture uptake, and a package insert for constitution and administration. Eligard package insert pdf eligard leuprolide acetate is indicated for the palliative due to incorrect reconstitution or administration of the product see monitoring. No drug dependence has been reported with the use of leuprolide. Firmagon can cause fetal harm when administered to a pregnant woman. Please see full prescribing information for additional important safety information. If blood appears in the syringe, the product should not be injected. The most common systemic adverse events include mild to severe hot flashessweats, malaise and fatigue, weakness, myalgia, dizziness, clamminess, testicular atrophy, and. Eligard leuprolide acetate for injectable suspension is a medicine for the treatment of advanced prostate cancer. On a clean field open both trays, discard the desiccant packs from each package and ensure all contents are in place.
Lupron depot leuprolide acetate for depot suspension 3. Highlights of prescribing information these highlights do. If blood appears in the syringe, the product can no longer be used. Minimum ppe required handling only no alteration contained crushsplit crushsplit minimum ppe required abacavir susp 2 ziagenepzicomtrizivir low abacavir tablet 2 ziagenepzicomtrizivir universal low moderate. Firmagon is contraindicated in patients with a known hypersensitivity to degarelix or to any of the product components and in women who are or may become pregnant. See the lupron depot ped package insert for the use of leuprolide acetate in children with central precocious puberty.
This emedtv resource explains why people who smoke or drink alcohol regularly may be at greater risk for problems with eligard. Get medical help right away if you get any of these symptoms. Read the patient information leaflet if available from your pharmacist before you start using leuprolide and each time you get a refill. Pull out the short blue plunger rod with attached gray stopper. Eligard 45 mg 6month the recommended dose of eligard 45 mg 6month is 45 mg administered every six months as a single subcutaneous injection after mixing with a special polymer formulation see administration. Anaphylactic reactions including anaphylactic shock to synthetic lhrh or lhrh analogs have been reported in postmarketing surveillance.
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